Group Group N (%) Aneuploidy (%) pCNV (%)
Ultrasonographic anomalies (N=133,12)
Gestational week
Gestational week
Gestational week
Gestational week
First trimester 736 (5.53%) 333 (45.24%) 39 (5.30%)
Second trimester 10,148 (76.23%) 501 (4.94%) 648 (6.39%)
Third trimester 2,428 (18.24%) 44 (1.81%) 144 (5.93%)
Num of ultrasonographic anomalies Num of ultrasonographic anomalies Num of ultrasonographic anomalies Num of ultrasonographic anomalies
1 11,818 (88.78%) 597 (5.05%) 671 (5.68%)
2 1,220 (9.16%) 202 (16.56%) 119 (9.75%)
≥ 3 274 (2.06%) 79 (28.83%) 41 (14.96%)
Total 13,312 (100%) 878 (6.60%) 831 (6.24%)
Soft markers (N=17,679)
Gestational week
Gestational week
Gestational week
Gestational week
First trimester 6,583 (37.24%) 873 (13.26%) 274 (4.16%)
Second trimester 9,775 (55.29%) 391 (4.00%) 326 (3.34%)
Third trimester 1,321 (7.47%) 16 (1.21%) 44 (3.33%)
Num of soft markers Num of soft markers Num of soft markers Num of soft markers
1 15,856 (89.69%) 1,107 (6.98%) 560 (3.53%)
2 1,704 (9.64%) 153 (8.98%) 77 (4.52%)
≥ 3 119 (0.67%) 20 (16.81%) 7 (5.88%)
Total 17,679 (100%) 1,280 (7.24%) 644 (3.64%)
Fetuses with no anomalies (N=12,730) Fetuses with no anomalies (N=12,730) 12,730 (100%) 321 (2.52%) 247 (1.94%)