Case presentation:
A 34-year-old woman was referred to our clinic complaining from
psoriasiform plaques (Figure1,2). The plaques were originated from 12
years ago in the multiple areas of the body and progressed gradually in
the extent of skin involvement. No associating signs were reported and
no other past medical, pharmacological, or family history were present.
Physical examination revealed multiple indurated, well-demarcated
erythematous plaques with thick psoriasiform scales all over the chest,
abdomen, back, and upper and lower extremities. Her face was nearly
spared with normal hair and nails. Neither lymphadenopathy nor other
systemic symptoms were found. Except for the cutaneous findings,
physical examination revealed normal findings of other organs. The
lesions on the affected skin area were biopsied and the pathology report
confirmed a diagnosis of MF and the presence of 60% neutrophils, 30%
lymphocytes (3% atypical), 8% monocytes, and 1% eosinophils. The
patient underwent PUVA therapy and weekly methotrexate injection, and
was prescribed with oral prednisolone 2.5 mg daily for the first month
followed by 1.25 mg daily during the next months, a topical ointment
including 90% ucerin and 10% urea once daily, and a topical ointment
of 50% clobetasol and 50% ucerin once every night. After one month of
the treatment significant improvement in all the lesions were
observed.After one year of the treatment the disease was completely
recovered and treatment with PUVA was significantly efficient
(Figure3,4).