Patient Age at onset of epilepsy Years since epilepsy onset Etiology Epilepsy syndrome (Inter)ictal EEG dominance Highest phase of epilepsy evaluation Earlier surgical inter-ventions Seizures/ month before DBS Medication (daily dose in mg)
#1 34 30 postencephalitis/ negative MRI bitemp. NA Phase II- FO - 12-14 lacosamide 400, lamotrigine 400, oxcarbamazepine 600
#2 12 5 unknown bitemp. right Phase II- FO, Strip - 12 carbamazepine CR 800, lamotrigine 300, clonazepam 0.5, clobasam 20, quetiapine 50
#3 15 23 left HS bitemp. left Phase II- FO - 4-5 carbamazepine CR 700, clobazam 20, zonisamide 200
#4 1 22 susp. Right cingular FCD bifront. left Phase I - 1 clobasam 30 mg, lacosamide 400 mg, lamotrigine 200 mg
#5 2 38 unknown multifocal fronto-temporal right Phase II- Strip - 2-4 zonisamide 300, lamotrigine 250
#6 11 32 bilateral HS bitemp. left Phase-I - 1-2 lamotrigine 300 mg, lacosamide 300 mg, cenobamate 400 mg
#7 18 18 bilat. parietal polymicrogyria, bilat. HS bitemp. right Phase II- FO VNS 14-20 levetiracetam 3000, carbamazepine 1500, zonisamide 400
#8 12 13 bilateral HS bitemp. NA Phase II- FO VNS 30 levetiracetam 3000 mg, lamotrigine 400 mg
#9 23 18 uncertain HS with left dominance bitemp. left Phase II- FO - 2-3 lacosamide 300, levetiracetam 1500
#10 12 34 assumed HS bitemp. left Phase II- FO right temporal resection 2-4 clobasam 20, oxcarbamazepine 600, lacosamide 400, topiramate 200
#11 27 12 left HS, postencephalitis multifocal fronto-temporal left Phase I. - 4 lamotrigine 400 mg, brivaracetam 100 mg
#12 20 19 bilat. subependymal heterotopia & non-regular hippocampal anatomy, left closed lip schizencephaly bitemp. right Phase I - 6-7 carbamazepine 1500, topiramate 100
#13 17 25 left temporal dysgenesis, peritrigonal heterotopy left fronto-temporal left Phase I left temporal resectio 2x, left peritrigonal heterotopy resectio 4-5 perampanel 10 mg, lacosamide 500 mg, gabapentin 1200 mg, alprazolam 1 mg
#14 19 7 bilat. PVNH bitemp. right Phase I - 2 oxcarbamazepine 1800, levetiracetam 2000, topiramate 300, sulthiam 300
#15 19 16 postencephalitis/ negative MRI left fronto-temporal left Phase II- Strip + Grid left temporal resection, VNS 6-10 clonazepam 2, lamotrigine 425, phenobarbital 100, risperidone 2.5
1bitemp – bitemporal; FO – foramen ovale electrodes; CR – controlled release; HS – hippocampal sclerosis; PVNH – periventricular nodular heterotopia; VNS – vagus nerve stimulation; DBS – deep brain stimulation; Phase I – video-EEG monitoring with scalp electrodes; Phase II –video-EEG with invasive electrodes 1bitemp – bitemporal; FO – foramen ovale electrodes; CR – controlled release; HS – hippocampal sclerosis; PVNH – periventricular nodular heterotopia; VNS – vagus nerve stimulation; DBS – deep brain stimulation; Phase I – video-EEG monitoring with scalp electrodes; Phase II –video-EEG with invasive electrodes 1bitemp – bitemporal; FO – foramen ovale electrodes; CR – controlled release; HS – hippocampal sclerosis; PVNH – periventricular nodular heterotopia; VNS – vagus nerve stimulation; DBS – deep brain stimulation; Phase I – video-EEG monitoring with scalp electrodes; Phase II –video-EEG with invasive electrodes 1bitemp – bitemporal; FO – foramen ovale electrodes; CR – controlled release; HS – hippocampal sclerosis; PVNH – periventricular nodular heterotopia; VNS – vagus nerve stimulation; DBS – deep brain stimulation; Phase I – video-EEG monitoring with scalp electrodes; Phase II –video-EEG with invasive electrodes 1bitemp – bitemporal; FO – foramen ovale electrodes; CR – controlled release; HS – hippocampal sclerosis; PVNH – periventricular nodular heterotopia; VNS – vagus nerve stimulation; DBS – deep brain stimulation; Phase I – video-EEG monitoring with scalp electrodes; Phase II –video-EEG with invasive electrodes 1bitemp – bitemporal; FO – foramen ovale electrodes; CR – controlled release; HS – hippocampal sclerosis; PVNH – periventricular nodular heterotopia; VNS – vagus nerve stimulation; DBS – deep brain stimulation; Phase I – video-EEG monitoring with scalp electrodes; Phase II –video-EEG with invasive electrodes 1bitemp – bitemporal; FO – foramen ovale electrodes; CR – controlled release; HS – hippocampal sclerosis; PVNH – periventricular nodular heterotopia; VNS – vagus nerve stimulation; DBS – deep brain stimulation; Phase I – video-EEG monitoring with scalp electrodes; Phase II –video-EEG with invasive electrodes 1bitemp – bitemporal; FO – foramen ovale electrodes; CR – controlled release; HS – hippocampal sclerosis; PVNH – periventricular nodular heterotopia; VNS – vagus nerve stimulation; DBS – deep brain stimulation; Phase I – video-EEG monitoring with scalp electrodes; Phase II –video-EEG with invasive electrodes 1bitemp – bitemporal; FO – foramen ovale electrodes; CR – controlled release; HS – hippocampal sclerosis; PVNH – periventricular nodular heterotopia; VNS – vagus nerve stimulation; DBS – deep brain stimulation; Phase I – video-EEG monitoring with scalp electrodes; Phase II –video-EEG with invasive electrodes 1bitemp – bitemporal; FO – foramen ovale electrodes; CR – controlled release; HS – hippocampal sclerosis; PVNH – periventricular nodular heterotopia; VNS – vagus nerve stimulation; DBS – deep brain stimulation; Phase I – video-EEG monitoring with scalp electrodes; Phase II –video-EEG with invasive electrodes