It was found that 6 /11 (54.5%) subjects did not report any adverse
outcomes and were uneventful pregnancies. There were 2 miscarriages.
Adverse events reported were consistent with background population
expectation, including: 1 postpartum hemorrhage, 1 case of preeclampsia,
1 preterm birth, 2 NICU admissions, and 2 caesarean sections. None of
the subjects gave birth to low birthweight (bwt) infants (Table 3A).
Overall, birthweights for gestational age (GA) fell between the
10th and 90th percentiles (%ile),
so all subjects in the Prazosin cohort exhibited fetal growth within the
normal population distribution. Looking at individual patient data as
shown in Table 3B, patient 1 experienced hemorrhaging (9.1%) and
required NICU (18.2%), patient 3 required a c-section (18.2%),
patients 4 and 7 experienced a miscarriage (18.2%), and patient 9
experienced pre-eclampsia (9.1%), required a c-section (18.2%),
required NICU (18.2%), and had a preterm baby (9.1%).
When the patients were asked about Pregnancy satisfaction, 8/11 (72.7%)
reported that they were satisfied and thought their pregnancies had gone
as smoothly as possible.