Posaconazole to fluconazole:
Posaconazole was switched to fluconazole in one case (Case 7, Table 1)
in the setting of potential drug interactions with venetoclax during
HSCT. This patients GGT peaked 10 days prior to the switch (137 IU/L,
2.8 x ULN) and remained elevated (113 IU/L) three days prior to switch
but had improved within 11 days post switch (GGT 42 IU/L, 1.1 x ULN).
However, the GGT began to uptrend reaching a peak of 290 IU/L 20 days
post switch in the context of HSCT.