Voriconazole to itraconazole:
The child that was switched from voriconazole to itraconazole had
supratherapeutic voriconazole concentrations 15 days prior (6.12 mg/L),
with associated LFT abnormalities and rash (Case 6, Table 1). The dose
was reduced by 16% however a repeat level was not taken. After the
switch to itraconazole the LFTs normalised by day 34.