Study design and populations
This was a national cross-sectional epidemiological study included
all-aged patients with AD who were diagnosed clinically by “Williams
diagnostic criteria” in the department of dermatology in respective
hospitals from 31/34 provincial administrative divisions in China
(Figure S1). Exclusion criteria comprised language or other barriers not
able to follow questions and give answers in a face to face interview.
The cross-sectional entries of patients were screened. Patients were
required to provide written informed consent prior to participation.
This research was registered in a publicly accessible database
(https://clinicaltrials.gov/,
ClinicalTrials.gov Identifier: NCT05316805, Cornerstone) and approved by
the ethics committees at country level.