Statistical analysis
Differences between continuous variables were tested for significance
using the independent-samples t -test. Differences between
categorical variables were tested for significance using the chi-squared
test or Fisher’s exact test, each as appropriate. All tests applied were
two-tailed and a P -value ≤0.05 was considered statistically
significant. Survival was analysed with Kaplan-Meier plots. Median
survival durations were reported with 95% confidence intervals (CI).
Differences between groups were tested using the Log-Rank test. The data
were analysed using R version 4.0.5 (R Foundation for Statistical
Computing, Vienna, Austria).