NOTE: Cerebrovascular Diseases: Ischemic stroke, TIA and Cerebral hemorrhage; Device-related outcomes: Device thrombus, Device migration and ≥5mm peri-device flow; Major bleeding: Cardiac effusion, Cardiac tamponade and Major bleeding event; Renal complications: Acute renal failure, Chronic renal failure, Renal insufficiency, Acute kidney injury and Cardiorenal syndrome.

Supplementary Table 7 . Publication bias and sensitivity analysis of primary outcomes.