2.3. Search Design
Two reviewers (Z.Y.Z and J.Z) independently searched the literature and
screen the titles, abstracts and full texts to select all relevant
studies that met the inclusion criteria. A study would be included if
the following criteria were met: (1) randomized controlled trials and
cohort, observational studies, and single-arm studies; (2)studies
comparing clinical outcomes comparing TEE vs. ICE for endocardial LAAO,
including efficacy outcome (e.g., procedural success) and safety
outcomes (e.g. short-term complications and long-term complications);
(3) studies with full text published in peer-reviewed journals; and
studies containing the most data for multiple publications of the same
study . Case reports, editorial, review articles, studies without
original data letters and studies reporting clinical outcomes with
hybrid LAAO procedures were excluded. Meanwhile, a third reviewer
(R.X.W) resolved any disagreements about eligibility