5.4 HNF4α8 (P2a-α8) protein partners
As for other HNF4α isoforms, little is known about the nature of protein interactions between P2a-α8 isoform and co-transcriptional regulators. One study showed that P2a-α8 could recruit transcription factor 4 (TCF4) directly on HNF4α DNA-binding elements, although no direct physical interaction between these proteins could be demonstrated [50].