5.3 HNF4α7 (P2a-α7) protein partners
A certain transcriptional synergy was reported between P2a-α7 and the
coactivators p300 and NCOA2, although the magnitude of transcriptional
activation was lesser when compared to P1a-α1 [58]. It was also
shown in the same report that NCOR2 was able to repress gene
transcription via interaction with P2a-α7 and the recruitment of HDAC4;
however, this repression activity was reduced when compared to P1a-α1.