3.3 | Prognostic demographic and clinicopathological
characteristics
Demographic and clinicopathological characteristics in the women with
LSIL (CIN1) preceded by AHPV positive/normal or mildly abnormal cytology
cohort are summarized in Table 2. In univariate analysis, sexual partner
(HR = 2.491; 95% CI, 1.073–5.784), enrolment cytology (HR = 2.339;
95% CI, 1.051–5.207) and AHPV-GT genotyping at baseline (HR = 4.155;
95% CI, 1.885–9.160) were all associated with the 2-year CIR of CIN2+
(all P < 0.05), while age at diagnosis, marital status,
childbearing, contraception, menopausal status, sexual debut and
enrolment cytology were excluded at P > 0.05. With
mutual adjustment, only AHPV-GT genotyping at baseline (HR = 3.462; 95%
CI, 1.546–7.749) was confirmed as an independent prognostic marker for
progression in the multivariate analysis (P = 0.003). In
univariate analysis, only AHPV-GT genotyping (HR = 5.153; 95% CI,
1.490–17.820) was associated with the 2-year CIR of CIN3+ (P =
0.010).