3.3 | Prognostic demographic and clinicopathological characteristics
Demographic and clinicopathological characteristics in the women with LSIL (CIN1) preceded by AHPV positive/normal or mildly abnormal cytology cohort are summarized in Table 2. In univariate analysis, sexual partner (HR = 2.491; 95% CI, 1.073–5.784), enrolment cytology (HR = 2.339; 95% CI, 1.051–5.207) and AHPV-GT genotyping at baseline (HR = 4.155; 95% CI, 1.885–9.160) were all associated with the 2-year CIR of CIN2+ (all P < 0.05), while age at diagnosis, marital status, childbearing, contraception, menopausal status, sexual debut and enrolment cytology were excluded at P > 0.05. With mutual adjustment, only AHPV-GT genotyping at baseline (HR = 3.462; 95% CI, 1.546–7.749) was confirmed as an independent prognostic marker for progression in the multivariate analysis (P = 0.003). In univariate analysis, only AHPV-GT genotyping (HR = 5.153; 95% CI, 1.490–17.820) was associated with the 2-year CIR of CIN3+ (P = 0.010).