Cardiofaciocutaneous syndrome is a rare genetic disorder. It is
characterized by craniofacial dysmorphism, congenital heart disease,
ectodermal abnormalities, developmental delay, and central nervous
system disorders. We discuss the case of an 11-year-old boy with
cardiofaciocutaneous syndrome presenting with ulerythema ophryogenes and
phenotypic features similar to Noonan syndrome.