Cohort characteristics
Mother and infant characteristics of the 704 offspring (352 intervention
group and 352 placebo) with data on atopic eczema at any of ages 12
(n=636), 24 (n=611) or 48 (n=450) months were similar in the
intervention and placebo groups with the exception of longer
breastfeeding duration in the intervention group (Table 1). Mother and
infant characteristics apart from breastfeeding duration were also
similar for the subgroups followed up at each of the three postnatal
ages (Supplementary Table 1), and the 704 mothers and offspring included
had characteristics similar to those of the overall group recruited to
MAVIDOS (Supplementary Table 2). Baseline maternal serum 25(OH)D levels
at recruitment in early pregnancy were similar in the intervention and
placebo groups. In late pregnancy, maternal serum 25(OH)D levels were
higher in the intervention group compared with the placebo group (Table
1).