Expressions of NKG2D ligands MICA and MICB are increased in JIA patients
The expressions of NKG2D ligands MICA and MICB in JIA patient subsets and healthy controls are presented in Figure 2. The contents of sMICA and sMICB were greatly increased in the different subgroups compared to the healthy controls (P<0.01). No differences were evident among the different subgroups of JIA patients (P>0.05). The expressions of MICA and MICB on DCs were significantly increased in paJIA and poJIA patients compared with healthy controls (P<0.05), but no difference between systemic JIA and the controls (P>0.05).