CD4+NKG2D+ T cells are activated in different subgroups of JIA patients
There were no statistical differences of age and gender among the different groups of JIA and the control group (P>0.05). The percentages of peripheral CD4+NKG2D+T cells in the different active subgroups and healthy control are shown in Figure 1. All JIA subgroups had a significantly higher proportion of CD4+NKG2D+ T cells than the healthy controls (P < 0.01). Systemic onset JIA (soJIA) patients displayed a significantly lower proportion of CD4+NKG2D+ T cells than paJIA and poJIA patients (P < 0.05). No statistical difference in the proportion of CD4+NKG2D+ T cells was evident between paJIA and poJIA patients (P>0.05).