Figure 1 CD4⁺NKG2D⁺ T cell activation in peripheral blood mononuclear cells (PBMCs) juvenile idiopathic arthritis (JIA) subtypes. Panels A and B are representative summary bar charts (A) and flow cytometry plots (B) showing the frequency of CD4⁺NKG2D⁺ T cells within total CD4⁺ cells in PBMCs from healthy controls (HC; n = 10) and active patients, including systemic onset JIA (soJIA; n = 10); pauciarticular JIA (paJIA; n = 8) and polyarticular JIA (poJIA; n = 8). * P < 0.01 and # P < 0.05 for within group interaction.