Conclusion
In summary, we report a case of SLE with lupus hepatitis and secondary
biliary tract involvement. During the diagnosis and treatment of SLE,
particularly in regions with a high prevalence of hepatitis B cirrhosis
like China, it is important to exclude hepatitis B or alcohol-related
liver injuries and also consider differential diagnosis from other
autoimmune liver diseases. Liver biopsy and liver fibrosis examination
are also necessary, especially for identifying unknown causes of liver
dysfunction and cirrhosis. Cholestasis provides a more comprehensive
diagnosis. Hormone therapy combined with immunosuppressive therapy is
recommended for these patients. In this case, the combined treatment of
methylprednisolone and mycophenolate has been implemented and has
demonstrated favorable results.