Patients
In this study, women who had undergone minimal stimulation protocol in
vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) in
the Clinical Center of Reproductive Medicine, First Affiliated Hospital
of Nanjing Medical University during January 1st, 2005 to December 31st,
2021 were considered for inclusion.
The inclusion criteria include: (1) women diagnosed with DOR (2) women
age between 20 to 45 years of age.
Exclusion criteria include: (1)
PGD/PGS cycles (2) patients with chromosomal/genetic disorders or
autoimmune diseases (3) patients with untreated severe endometriosis or
intrauterine adhesion. For the propose of this study, women with the
same inclusion and exclusion criteria who and undergone conventional
ovarian stimulation protocol were also included.