Continuous blood purification successfully treated a fatal cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome after chimeric antigen receptor T cell therapy: case report
Feng Zhang1, Xin-lei Jia, MD2, Ying-xi Zuo, MD1, Ai-dong Lu, MD1, Peng-fei Zhang, 2 Lian Xue, MD1, Le-ping Zhang, MD1*
1.Department of Pediatrics, Peking University People’s Hospital, China
2.Department of Pediatrics Intensive Care Unit, Beijing Children’s Hospital, Capital Medical University, China
* Correspondence to:
Le-ping Zhang, MD, Department of Pediatrics, Peking University People’s Hospital Email: zhangleping@pkuph.edu.cn
Text word count; 2045
Abstract word count: 99;
Brief running title: blood purification treated a fatal CRS after CAR-T
Key words: cytokine release syndrome, Immune effector Cell-Associated Neurotoxicity Syndrome, therapeutic plasma exchange, continuous renal replacement treatment
Tables: 1
Figures: 2