Tweetable statement
Fetal growth restriction (FGR) is the leading cause of intrauterine fetal death, neonatal death, and short-term and long-term complications worldwide. It is difficult to evaluate the potential growth of a fetus. Therefore, different countries and associations have developed different guidelines to screen for fetuses with suspected FGR. The purpose of this study was to compare the ability of different FGR definitions to predict small-for-gestational-age (SGA) and adverse neonatal outcomes (ANO), so as to figure out a more suitable definition for Chinese population.
In this respective study, a total of 2340 cases were included. Among them, 115 (4.9%), 63 (2.7%), and 48 (2.1%) cases of FGR were diagnosed using the diagnostic criteria issued by the SMFM, ACOG, and ISUOG respectively. There were 147 (6.28%) cases of SGA neonates. The SMFM criteria had higher sensitivity (40.82% vs 24.49%, 20.41%) for SGA compared to the ACOG and ISUOG criteria. All three definitions had low sensitivity for ANO (17.32%, 12.6%, 11.81%) and high specificity of 95.8%, 97.88% and 98.51%. The AUCs of SMFM for predicting SGA (0.692) and ANO (0.566) were slightly higher than those of ACOG (0.616, 0.552) and ISUOG (0.598, 0.552).