Tweetable statement
Fetal
growth restriction (FGR) is the leading cause of intrauterine fetal
death, neonatal death, and short-term and long-term complications
worldwide. It is difficult to evaluate the potential growth of a fetus.
Therefore, different countries and associations have developed different
guidelines to screen for fetuses with suspected FGR. The purpose of this
study was to compare the ability of different FGR definitions to predict
small-for-gestational-age (SGA) and adverse neonatal outcomes (ANO), so
as to figure out a more suitable definition for Chinese population.
In this respective study, a total of 2340 cases were included. Among
them, 115 (4.9%), 63 (2.7%), and 48 (2.1%) cases of FGR were
diagnosed using the diagnostic criteria issued by the SMFM, ACOG, and
ISUOG respectively. There were 147 (6.28%) cases of SGA neonates. The
SMFM criteria had higher sensitivity (40.82% vs 24.49%, 20.41%) for
SGA compared to the ACOG and ISUOG criteria. All three definitions had
low sensitivity for ANO (17.32%, 12.6%, 11.81%) and high specificity
of 95.8%, 97.88% and 98.51%. The AUCs of SMFM for predicting SGA
(0.692) and ANO (0.566) were slightly higher than those of ACOG (0.616,
0.552) and ISUOG (0.598, 0.552).