Innate immune response
|
(a) The development and research of vaccines are mainly based on
inhibiting the bacterial immune evasion from innate immune responses,
for example, targeting virulence factors by blocking the complement
system and killing neutrophils.
(b) AAC therapy facilitates bacterial uptake by phagocytic cells through
opsonizing by antibodies.
|
(a) Targeting the complement system: They influence the complement
system to regulate the development of MRSA infection.
(b) Targeting neutrophil phagocytosis: They act on neutrophil migration
and recruitment, chemokine expression, macrophage activity and antigen
presentation.
|