Figure 7. Nucleotide alignment of the FLO5 gene in the BTCC3, F118 and S288C strains. Codons shown in the red boxes indicate genetic variations causing amino acid replacements in the PA14 domain (Line 1) and frameshift mutations in tandem repeat regions (Lines 2 and 3) (a). Domain structure of the flocculin Flo5 protein inSaccharomyces cerevisiae (b). Protein alignment of the flocculin Flo5 protein in the BTCC3, F118 and S288C strains (c).