Fig 5. pSS plasma, IgG and IgA down-regulate the viability of
pDCs.
a. Representative flow cytometric graph and summary graph of
pDCs viability. pDCs were stimulated by HC or pSS derived plasma (n=5)
for 4 hours with 100ng/ml IL3. Representative flow cytometric graph of
apoptosis detection, pDCs were stimulated by increasing concentration of
IgG (b) or IgA (c) for 2 hours with 100ng/ml IL3
(n=4). Statistical graph of pDCs viability when stimulated by different
concentrations of human IgG (d) and IgA (e) . Unpaired
two-tailed Student’s t-test was performed. *P-value < 0.05,
**P-value < 0.01, ***P-value <0.001, **** P-value
<0.0001.