Patients and ethics
All newly-onset pSS and SLE patients were enrolled in Peking Union
Medical College Hospital (PUMCH) and met the 2016 ACR-EULAR
classification[22] and the 1997 classification criteria of the
American College of Rheumatology[23], respectively. Labial tissues
were obtained from patients who underwent labial gland biopsy at the
department of stomatology in PUMCH. Patients all signed informed consent
for their residual tissues after the pathological examination. This
study was approved by the Ethics Committee of PUMCH (No: K2525).