3.5.2 Cell cycle
In the CNS, we found small, coordinated upregulation of genes belonging to functional categories involved in the cell cycle, and genes positively correlated with CO2 treatment and all three activity traits were enriched for cell cycle functional categories (Table 3, Figures 3 and 5). This included genes and functional categories involved in regulating the cell cycle, as well as those specifically involved in the cell cycle stages of interphase and mitosis. In particular, there was small, coordinated upregulation of genes belonging to the functional categories ‘chromosome’ and ‘protein kinase binding’ (Figure 3), and these same functions were enriched in the genes positively correlated with CO2 treatment and all three activity traits (Figure 5).