3.5.2 Cell cycle
In the CNS, we found small, coordinated upregulation of genes belonging
to functional categories involved in the cell cycle, and genes
positively correlated with CO2 treatment and all three
activity traits were enriched for cell cycle functional categories
(Table 3, Figures 3 and 5). This included genes and functional categories
involved in regulating the cell cycle, as well as those specifically
involved in the cell cycle stages of interphase and mitosis. In
particular, there was small, coordinated upregulation of genes belonging
to the functional categories ‘chromosome’ and ‘protein kinase binding’
(Figure 3), and these same functions were enriched in the genes
positively correlated with CO2 treatment and all three
activity traits (Figure 5).