Representativeness of cases |
Representativeness of
cases |
|
|
Consecutive/randomly selected form case population with a clearly
defined sampling frame |
2 |
|
Consecutive/randomly selected form case population without a clearly
defined sampling frame or with extensive |
1 |
|
Not described |
0 |
Source of controls |
Source of controls |
|
|
Population- or Healthy-based |
2 |
|
Hospital-bases |
1 |
|
Not described |
0 |
Hardy-Weinberg equilibrium in controls |
Hardy-Weinberg
equilibrium in controls |
|
|
Hardy-Weinberg equilibrium |
2 |
|
Hardy-Weinberg disequilibrium |
1 |
|
Not available |
0 |
Genotyping examination |
Genotyping examination |
|
|
Genotyping done under ”blinded” condition and repeated again |
2 |
|
Genotyping done under ”blinded” condition or repeated again |
1 |
|
Un-blinded done or not mentioned and unrepeated |
0 |
Association assessment |
Association assessment |
|
|
Assess association between genotypes and cancer with appropriate
statistics and adjustment for confounders |
2 |
|
Assess association between genotypes and cancer with appropriate
statistics and without adjustment for confounders |
1 |
|
Inappropriate statistics used |
0 |
Total Score |
Total Score |
10 |