Model
Number of studies
Test of association
Test of association
Test of association
Test of association
Test of heterogeneity
Test of heterogeneity
Publication bias
OR 95% CI p-val Model p-val I2 p-val (Egger’s test)
Allelic model (del vs. ins) Allelic model (del vs. ins) Allelic model (del vs. ins)
Overall 10 0.98 [0.8024; 1.1941] 0.83 Random 0.00 0.94 0.62
Type of cancer
Colorectal 2 1.04 [0.6035; 1.8090] 0.88 Random 0.00 0.97 NA
Gastric 2 0.78 [0.6916; 0.8701] 0.00 Fixed 0.20 0.40 NA
Source of control
HB 7 0.99 [0.7614; 1.2833] 0.93 Random 0.00 0.94 0.62
PB 3 0.95 [0.6606; 1.3705] 0.79 Random 0.00 0.95 0.87
Recessive model (del/del vs. del/ins+ ins/ins) Recessive model (del/del vs. del/ins+ ins/ins) Recessive model (del/del vs. del/ins+ ins/ins) Recessive model (del/del vs. del/ins+ ins/ins) Recessive model (del/del vs. del/ins+ ins/ins)
Overall 10 1.09 [0.7822; 1.5251] 0.60 Random 0.00 0.88 0.65
Type of cancer
Colorectal 2 1.14 [0.4599; 2.8040] 0.78 Random 0.00 0.95 NA
Gastric 2 0.73 [0.5565; 0.9603] 0.02 Fixed 0.43 0.00 NA
Source of control
HB 7 1.14 [0.7453; 1.7457] 0.54 Random 0.00 0.88 0.75
PB 3 0.99 [0.5133; 1.8995] 0.97 Random 0.00 0.92 0.69
Dominant model (del/del+ del/ins vs. ins/ins) Dominant model (del/del+ del/ins vs. ins/ins) Dominant model (del/del+ del/ins vs. ins/ins) Dominant model (del/del+ del/ins vs. ins/ins) Dominant model (del/del+ del/ins vs. ins/ins)
Overall 10 0.95 [0.7571; 1.2016] 0.69 Random 0.00 0.92 0.74
Type of cancer
Colorectal 2 1.04 [0.5500; 1.9623] 0.91 Random 0.00 0.96 NA
Gastric 2 0.73 [0.6278; 0.8404] 0.00 Fixed 0.29 0.09 NA
Source of control
HB 7 0.97 [0.7099; 1.3132] 0.82 Random 0.00 0.92 0.68
PB 3 0.92 [0.6108; 1.3874] 0.69 Random 0.00 0.93 0.97
Over-dominant model ( del/ins vs. del/del+ ins/ins) Over-dominant model ( del/ins vs. del/del+ ins/ins) Over-dominant model ( del/ins vs. del/del+ ins/ins) Over-dominant model ( del/ins vs. del/del+ ins/ins) Over-dominant model ( del/ins vs. del/del+ ins/ins) Over-dominant model ( del/ins vs. del/del+ ins/ins)
Overall 10 0.93 [0.8199; 1.0549] 0.26 Random 0.00 0.71 0.53
Type of cancer
Colorectal 2 0.98 [0.7166; 1.3284] 0.88 Random 0.01 0.85 NA
Gastric 2 0.79 [0.6809; 0.9161] 0.00 Fixed 0.45 0.00 NA
Source of control
HB 7 0.93 [0.7830; 1.1127] 0.44 Random 0.00 0.75 0.47
PB 3 0.91 [0.7521; 1.1032] 0.34 Random 0.04 0.70 0.95
Homozygote contrast model (del/del vs. ins/ins) Homozygote contrast model (del/del vs. ins/ins) Homozygote contrast model (del/del vs. ins/ins) Homozygote contrast model (del/del vs. ins/ins) Homozygote contrast model (del/del vs. ins/ins)
Overall 10 1.06 [0.6964; 1.6162] 0.78 Random 0.00 0.92 0.68
Type of cancer
Colorectal 2 1.15 [0.3629; 3.6704] 0.81 Random 0.00 0.97 NA
Gastric 2 0.64 [0.4861; 0.8529] 0.00 Fixed 0.38 0.00 NA
Source of control
HB 7 1.11 [0.6484; 1.9116] 0.70 Random 0.00 0.92 0.76
PB 3 0.94 [0.4190; 2.1301] 0.89 Random 0.00 0.94 0.74
Additive model (del/del vs. ins/del) Additive model (del/del vs. ins/del) Additive model (del/del vs. ins/del) Additive model (del/del vs. ins/del)
Overall 10 1.15 [0.9055; 1.4682] 0.25 Random 0.00 0.74 0.74
Type of cancer
Colorectal 2 1.13 [0.5977; 2.1423] 0.70 Random 0.00 0.89 NA
Gastric 2 0.86 [0.6475; 1.1475] 0.31 Fixed 0.67 0.00 NA
Source of control
HB 7 1.21 [0.8941; 1.6358] 0.22 Random 0.00 0.73 0.87
PB 3 1.04 [0.6414; 1.6999] 0.86 Random 0.00 0.84 0.64
Heterozygote contrast model (del/ins vs. ins/ins) Heterozygote contrast model (del/ins vs. ins/ins) Heterozygote contrast model (del/ins vs. ins/ins) Heterozygote contrast model (del/ins vs. ins/ins) Heterozygote contrast model (del/ins vs. ins/ins)
Overall 10 0.94 [0.7744; 1.1403] 0.53 Random 0.00 0.87 0.69
Type of cancer
Colorectal 2 1.01 [0.6033; 1.7019] 0.96 Random 0.00 0.94 NA
Gastric 2 0.75 [0.6394; 0.8683] 0.00 Fixed 0.40 0.00 NA
Source of control
HB 7 0.95 [0.7299; 1.2315] 0.69 Random 0.00 0.88 0.62
PB 3 0.91 [0.6576; 1.2645] 0.58 Random 0.00 0.89 1.00