3.2.6 Levels of chromosome damage in the offspring
Table 7 presents the results of the micronucleus test in the female and
male offspring, evaluating whether the consumption of fructose and the
practice of voluntary physical exercise in the mothers causes mutagenic
effects in the bone marrow cells of the offspring.
Significantly higher levels of MnPCE were observed in the female and
male offspring from mothers treated with FRU in comparison to the water
group (p<0.05). Regarding the PCE/NCE ratio, no statistically
significant differences were observed between the groups, demonstrating
that the production of erythrocytes was occurring normally in the bone
marrow, with no evidence of cytotoxicity.