3.1.4 Levels of chromosome damage
To evaluate whether the consumption of fructose and the practice of
voluntary physical exercise causes additional genotoxic effects in the
mothers in the post-pregnancy period, the micronucleus test was
performed on bone marrow cells (Table 3).
Significantly higher levels of MnPCE were observed in mothers treated
with FRU in comparison to the water group (p<0.05). In
addition, a decrease in the number of MnPCE was observed in the FRU+VPE,
FRU+VPE/Water + VPE and FRU+VPE/Water group compared to the FRU group
(p<0.05). Regarding the PCE/NCE ratio, no statistically
significant differences were observed between the groups, demonstrating
that the production of erythrocytes was occurring normally in the bone
marrow, with no evidences of cytotoxicity.