3.2.3 Fasting blood glucose and insulin sensitivity of the offspring
The glycemic profile was evaluated in the offspring (females and males) through fasting glucose (Table 6) and the insulin tolerance test (Figure 9).
A decrease in fasting glucose was observed in offspring females in the FRU+VPE/Water+VPE group compared to the FRU group and FRU+VPE (p<0.05). In males, no significant differences were observed.
In the oral insulin tolerance test (figure 9), no significant differences were found in females, showing that the offspring were not insulin resistant. In offspring males, we observed a decrease in the area under the curve in the FRU+VPE/Water+VPE group compared to the fructose group and the FRU+VPE group (p<0.05). However, the fructose group did not demonstrated insulin resistance.