3.2.6 Levels of chromosome damage in the offspring
Table 7 presents the results of the micronucleus test in the female and male offspring, evaluating whether the consumption of fructose and the practice of voluntary physical exercise in the mothers causes mutagenic effects in the bone marrow cells of the offspring.
Significantly higher levels of MnPCE were observed in the female and male offspring from mothers treated with FRU in comparison to the water group (p<0.05). Regarding the PCE/NCE ratio, no statistically significant differences were observed between the groups, demonstrating that the production of erythrocytes was occurring normally in the bone marrow, with no evidence of cytotoxicity.