Participants
Eleven participants including
five untreated patients diagnosed as PD (PD group) and six healthy
volunteers as controls (HC group) underwent
[11C]CFT total-body PET/CT scans in our department
from January to December 2021. The neurologic assessment for patients
including the third part of Uniļ¬ed Parkinson Disease Rating Scale (UPDRS
III), modified Hoehn and Yahr stage (mH-Y), and Non-motor Symptoms Scale
(NMSS) were recorded. The detailed characteristics of all participants
were listed in Table 1 . Healthy volunteers were sourced from
health screening participants with no history of significant medical,
neuropsychiatric illnesses, or neoplastic diseases, which were excluded
using [18F]FDG PET/CT. This retrospective study
followed the principles of the Declaration of Helsinki and has been
approved by the ethics committee of Renji Hospital with written informed
consent waived.