Characterization of SUVmean curve
The SUVmean curves of descending aorta and occipital
lobe in the HC and PD groups were depicted in Figure 2A andB , demonstrating negligible difference in curve pattern of both
regions between the two groups. As the time went on, the ascending
curves of the brain nuclei in the two groups started to separate: while
the [11C]CFT uptake of HC group kept increasing,
the uptake of PD group tended to reach the “plateau” in advance
(Figure 2C , Table 2 ). In putamen,
[11C]CFT uptake of the two groups first showed an
early distinction (separation time = 2 min),
and the statistical significance was
found in the highest SUVmean between the two groups
(P <0.05).
The SUVmean curve patterns of the pancreas and duodenum
could be characterized as “fast-in and slow-out” in both groups, where
the peak activities of the HC group in these two organs were higher than
the PD group. In the stomach, a relatively faster rising uptake in PD
patients was observed in the early stage, yet the final
SUVmean of the HC group at 75 min appeared to be higher
(Figure 2D and Table 2) .