AUC _0-t, area under the curve from time 0 to the last measurable concentration; carotegrast-gluc, carotegrast glucuronate; CI, confidence interval; C_max, maximum drug concentration; CO_RIFAMPICIN, coadministration with rifampicin (600 mg); max, maximum; min, minimum; S_AJM300, single oral administration of carotegrast methyl (960 mg); SD: standard deviation; t_1/2, half-life period; T_max, time to C_max maximum drug concentration