4. CLINICAL APPLICATIONS OF PSYCHEDELICS FOR PAIN: CURRENT
KNOWLEDGE
Early research beginning in the 1950s was focused on ways in which
psychedelics could be used as an adjunctive to facilitate engagement in
psychotherapeutic interventions. Regulatory restrictions on psychedelics
in the early 1970s halted research. For chronic pain treatment,
psychedelics have mainly been investigated in palliative care,
cancer-related pain, headaches, and phantom limb pain.