Limitation
Our study has several limitations.
1. Because EH cannot be detected pathologically in vivo, the presence of
EH cannot be confirmed through pathological means in this study.
Therefore, animal experiments are necessary to further validate our
hypothesis.
2. Our study was limited by the absence of a healthy control group, and
previous research has indicated that unilateral MD may progress to
bilateral involvement over time19. Although no EH or
hearing loss were detected in the unaffected side of our patients, it is
possible that some microscopic structures have undergone changes, which
could potentially impact the precision of our findings.