Author/Year Trial group interventions Trial group interventions Trial group interventions C: Interventions Main outcome indicators Secondary outcome indicators gauge
Specific measures Frequency and Periodicity Systems/platforms
Cao/202314 VR United Minds March VR Glasses (Model MN391) routine care ①② ⑧⑫ T-DAS, EORTC QLQC30, self-made Satisfaction Questionnaire
Shin MD/202315 Receive virtual reality-based explanations of radiotherapy procedures in addition to standard information 7-8 min/session, 3 assessment time points Oculus Quest Wireless Virtual Reality Headset Routine health education on radiotherapy APAIS, STAI and LASA
Zhang/202216 VR-CALM, immersion in landscapes such as the seaside and Butterfly Valley, where patients can walk around, hear the wind and touch butterflies 30min/trip, 6 times in total (Headgear and controller) routine care ①②③ ⑤⑥ FACT-B, DT, CARS, PFS, PSQI, SAS, SDS
Chirico/201918 Immersive and interactive virtual reality For chemotherapy, ≥20 minutes Head-mounted glasses (Vuzix Wrap 1200 VR) and head movement tracking system Music therapy/ conventional chemotherapy ② ③ ⑤ SAI, SV- POMS, VRSQ
Mohammad/201819 drug + virtual reality sessions. 15 min/dose at time of administration, 4 months Virtual environments, distraction interventions drug analgesia ② ④ (vii) VAS, SAI, MMSE
Reynolds/202217 Virtual environment ”Happy Place + Ripples”, home intervention, measured at 6 different time points 4 weeks, 6 assessment time points VR headset + headphones Virtual environment ”Ripple + Happy Place”, home-based intervention ② ③ ④ ⑤ ⑨ EQ-5D-5L, VAS, FACIT-Fatigue, BPI, DASS-SF