References
1. Mathur P, Sathishkumar K, Chaturvedi M, Das P, Sudarshan KL,
Santhappan S, et al. Cancer statistics, 2020: report from national
cancer registry programme, India. JCO Global oncology. 2020;6:1063-75.
2. Nenclares P, Harrington K. The biology of cancer. Medicine.
2020;48(2):67-72.
3. ArefNezhad R, Rezaei‐Tazangi F, Roghani‐Shahraki H, Goleij P, Zare N,
Motedayyen H, et al. Human umbilical cord mesenchymal stem cells:
Heralding an effective treatment against esophageal cancer? Cell Biology
International. 2023;47(4):714-9.
4. Kontomanolis EN, Koutras A, Syllaios A, Schizas D, Mastoraki A,
Garmpis N, et al. Role of oncogenes and tumor-suppressor genes in
carcinogenesis: a review. Anticancer research. 2020;40(11):6009-15.
5. Fathi F, Saidi RF, Banafshe HR, Arbabi M, Lotfinia M, Motedayyen H.
Changes in immune profile affect disease progression in hepatocellular
carcinoma. International Journal of Immunopathology and Pharmacology.
2022;36:03946320221078476.
6. Wu S, Zhu W, Thompson P, Hannun YA. Evaluating intrinsic and
non-intrinsic cancer risk factors. Nature communications.
2018;9(1):1-12.
7. Hasan-Abad AM, Adabi E, Sadroddiny E, Khorramizadeh MR, Mazlomi MA,
Mehravar S, et al. Functional Deimmunization of Interferon Beta-1b by
Identifying and Silencing Human T Cells Epitopes. Iranian Journal of
Allergy, Asthma and Immunology. 2019:427-40.
8. Mavragani IV, Nikitaki Z, Kalospyros SA, Georgakilas AG. Ionizing
radiation and complex DNA damage: from prediction to detection
challenges and biological significance. Cancers. 2019;11(11):1789.
9. Rezaei-Tazangi F, Roghani-Shahraki H, Khorsand Ghaffari M, Abolhasani
Zadeh F, Boostan A, ArefNezhad R, et al. The therapeutic potential of
common herbal and nano-based herbal formulations against ovarian cancer:
New insight into the current evidence. Pharmaceuticals.
2021;14(12):1315.
10. Azevedo MM, Pina-Vaz C, Baltazar F. Microbes and cancer: friends or
faux? International Journal of Molecular Sciences. 2020;21(9):3115.
11. Sisakht M, Mahmoodzadeh A, Zahedi M, Rostamzadeh D, Hasan-Abad AM,
Atapour A. In silico approach for designing a novel recombinant fusion
protein as a candidate vaccine against hpv. Current Proteomics.
2021;18(4):549-62.
12. Zhao H, Wu L, Yan G, Chen Y, Zhou M, Wu Y, et al. Inflammation and
tumor progression: Signaling pathways and targeted intervention. Signal
transduction and targeted therapy. 2021;6(1):1-46.
13. Kay M, Hasan-Abad AM, Hojati Z, Korbekandi H. Targeted mutations in
Val101 and Arg27 interferon beta protein increase its transcriptional
and translational activities. Cytokine. 2016;78:1-6.
14. Abdel-Salam IM, Abou-Bakr A, Ashour M. Cytotoxic effect of aqueous
ethanolic extract of Luffa cylindrica leaves on cancer stem cells
CD44+/24-in breast cancer patients with various molecular sub-types
using tissue samples in vitro. Journal of ethnopharmacology.
2019;238:111877.
15. Baraya YuSaB, Wong KK, Yaacob NS. The immunomodulatory potential of
selected bioactive plant-based compounds in breast cancer: a review.
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal
Chemistry-Anti-Cancer Agents). 2017;17(6):770-83.
16. Chen H, Yang J, Yang Y, Zhang J, Xu Y, Lu X. The natural products
and extracts: anti‐triple‐negative breast cancer in vitro. Chemistry &
Biodiversity. 2021;18(7):e2001047.
17. Chowjarean V, Sadabpod K. Antiproliferative effect of
Grammatophyllum speciosum ethanolic extract and its bioactive compound
on human breast cancer cells. The Scientific World Journal. 2021;2021.
18. Chellappan DK, Chellian J, Ng ZY, Sim YJ, Theng CW, Ling J, et al.
The role of pazopanib on tumour angiogenesis and in the management of
cancers: A review. Biomedicine & Pharmacotherapy. 2017;96:768-81.
19. Kasiri N, Rahmati M, Ahmadi L, Eskandari N, Motedayyen H.
Therapeutic potential of quercetin on human breast cancer in different
dimensions. Inflammopharmacology. 2020;28:39-62.
20. Churiyah C, Ningsih S, Firdayani F. The cytotoxic, apoptotic
induction, and cell cycle arrest activities of solanum nigrum L.
ethanolic extract on MCF-7 human breast cancer cell. Asian Pacific
Journal of Cancer Prevention: APJCP. 2020;21(12):3735.
21. Keyvani V, Riahi E, Yousefi M, Esmaeili S-A, Shafabakhsh R, Moradi
Hasan-Abad A, et al. Gynecologic Cancer, Cancer Stem Cells, and Possible
Targeted Therapies. Frontiers in pharmacology. 2022;13:823572.
22. Alharbi KS, Shaikh MAJ, Almalki WH, Kazmi I, Al-Abbasi FA, Alzarea
SI, et al. PI3K/Akt/mTOR pathways inhibitors with potential prospects in
non-small-cell lung cancer. Journal of Environmental Pathology,
Toxicology and Oncology. 2022;41(4).
23. Colamba Pathiranage V, Lowe JN, Rajagopalan U, Ediriweera MK,
Senathilake K, Piyathilaka P, et al. Hexane extract of Garcinia quaesita
fruits induces apoptosis in breast cancer stem cells isolated from
triple negative breast cancer cell line MDA-MB-231. Nutrition and
Cancer. 2021;73(5):845-55.
24. Collard M, Gallagher PE, Tallant EA. A polyphenol-rich extract from
muscadine grapes inhibits triple-negative breast tumor growth.
Integrative Cancer Therapies. 2020;19:1534735420917444.
25. Gupta G, Al-Malki WH, Kazmi I, Thangavelu L, Gupta PK, Jha NK, et
al. The role of HGF/MET in liver cancer. Future medicinal chemistry.
2021;13(21):1829-32.
26. Dandawate PR, Subramaniam D, Jensen RA, Anant S, editors. Targeting
cancer stem cells and signaling pathways by phytochemicals: Novel
approach for breast cancer therapy. Seminars in cancer biology; 2016:
Elsevier.
27. Dhouibi R, Affes H, Salem MB, Hammami S, Sahnoun Z, Zeghal KM, et
al. Screening of pharmacological uses of Urtica dioica and others
benefits. Progress in biophysics and molecular biology. 2020;150:67-77.
28. Espinosa-Paredes DA, Cornejo-Garrido J, Moreno-Eutimio MA,
Martínez-Rodríguez OP, Jaramillo-Flores ME, Ordaz-Pichardo C. Echinacea
angustifolia DC extract induces apoptosis and cell cycle arrest and
synergizes with paclitaxel in the MDA-MB-231 and MCF-7 human breast
cancer cell lines. Nutrition and cancer. 2021;73(11-12):2287-305.
29. George BP, Chandran R, Thamburaj S, Parimelazhagan T. Combined
Effect of Vaccinium nilgiriensis Bark Extract and 680nm Laser
Irradiation in Inducing Breast Cancer Cell Death. Anti-Cancer Agents in
Medicinal Chemistry (Formerly Current Medicinal Chemistry-Anti-Cancer
Agents). 2021;21(2):207-13.
30. Graidist P, Martla M, Sukpondma Y. Cytotoxic activity of Piper
cubeba extract in breast cancer cell lines. Nutrients.
2015;7(4):2707-18.
31. Guerra AR, Soares BI, Freire CS, Silvestre AJ, Duarte MF, Duarte IF.
Metabolic effects of a Eucalyptus bark lipophilic extract on triple
negative breast cancer and nontumor breast epithelial cells. Journal of
Proteome Research. 2020;20(1):565-75.
32. Vinogradov S, Wei X. Cancer stem cells and drug resistance: the
potential of nanomedicine. Nanomedicine. 2012;7(4):597-615.
33. Patra CR, Mukherjee S, Kotcherlakota R. Biosynthesized silver
nanoparticles: a step forward for cancer theranostics? Nanomedicine.
2014;9(10):1445-8.
34. Mukherjee S, Patra CR. Therapeutic application of anti-angiogenic
nanomaterials in cancers. Nanoscale. 2016;8(25):12444-70.
35. Mohammadi M, Moradi Hasan-Abad A, Dehghani P, Nabipour I, Roozbehani
M, Hemphill A, et al. Dicentracin-Like from Asian sea bass fish and
Moronecidine-Like from Hippocampus comes: Two candidate antimicrobial
peptides against Leishmanina major infection. International Journal of
Peptide Research and Therapeutics. 2021;27:769-78.
36. Caruso M, Colombo A, Fedeli L, Pavesi A, Quaroni S, Saracchi M, et
al. Isolation of endophytic fungi and actinomycetes taxane producers.
Annals of microbiology. 2000;50(1):3-14.
37. Weaver BA. How Taxol/paclitaxel kills cancer cells. Molecular
biology of the cell. 2014;25(18):2677-81.
38. Hasan-Abad AM, Mohammadi M, Mirzaei H, Mehrabi M, Motedayyen H,
Arefnezhad R. Impact of oligomerization on the allergenicity of
allergens. Clinical and Molecular Allergy. 2022;20(1):1-10.
39. Aung TN, Qu Z, Kortschak RD, Adelson DL. Understanding the
effectiveness of natural compound mixtures in cancer through their
molecular mode of action. International journal of molecular sciences.
2017;18(3):656.
40. Singh S, Sharma B, Kanwar SS, Kumar A. Lead phytochemicals for
anticancer drug development. Frontiers in plant science. 2016;7:1667.
41. Newman DJ, Cragg GM. Natural products as sources of new drugs over
the nearly four decades from 01/1981 to 09/2019. Journal of natural
products. 2020;83(3):770-803.
42. Yuan H, Ma Q, Ye L, Piao G. The traditional medicine and modern
medicine from natural products. Molecules. 2016;21(5):559.
43. Cragg GM, Pezzuto JM. Natural products as a vital source for the
discovery of cancer chemotherapeutic and chemopreventive agents. Medical
Principles and Practice. 2016;25(Suppl. 2):41-59.
44. Seca AM, Pinto DC. Plant secondary metabolites as anticancer agents:
successes in clinical trials and therapeutic application. International
journal of molecular sciences. 2018;19(1):263.
45. Tariq A, Sadia S, Pan K, Ullah I, Mussarat S, Sun F, et al. A
systematic review on ethnomedicines of anti‐cancer plants. Phytotherapy
Research. 2017;31(2):202-64.
46. Thakore P, Mani RK, Kavitha SJ. A brief review of plants having
anti-cancer property. Int J Pharm Res Dev. 2012;3:129-36.
47. Choudhari AS, Mandave PC, Deshpande M, Ranjekar P, Prakash O.
Phytochemicals in cancer treatment: From preclinical studies to clinical
practice. Frontiers in pharmacology. 2020;10:1614.
48. Jafri A, Amjad S, Bano S, Kumar S, Serajuddin M, Arshad M. Efficacy
of nano-phytochemicals over pure phytochemicals against various cancers:
Current trends and future prospects. Nanomaterials and environmental
biotechnology. 2020:407-24.
49. Santos CD, Schier CJG. Colchicine, podophyllin, and the vinca
alkaloids. Goldfrank’s toxicologic emergencies, Eleventh Edition,
Eleventh New York: The McGraw-Hill Companies. 2019:501-10.
50. Zan L, Chen Q, Zhang L, Li X. Epigallocatechin gallate (EGCG)
suppresses growth and tumorigenicity in breast cancer cells by
downregulation of miR-25. Bioengineered. 2019;10(1):374-82.
51. Kim J, Yoo J, Kim J, Kim S, Park J, Seok Y, et al. Anticancer effect
of mountain ginseng. Evid Based Complement Alternat Med. 2020.
52. Garvin S, Öllinger K, Dabrosin C. Resveratrol induces apoptosis and
inhibits angiogenesis in human breast cancer xenografts in vivo. Cancer
letters. 2006;231(1):113-22.
53. Lai H-W, Chien S-Y, Kuo S-J, Tseng L-M, Lin H-Y, Chi C-W, et al. The
potential utility of curcumin in the treatment of HER-2-overexpressed
breast cancer: an in vitro and in vivo comparison study with herceptin.
Evidence-Based Complementary and Alternative Medicine. 2012;2012.
54. Xu J, Long Y, Ni L, Yuan X, Yu N, Wu R, et al. Anticancer effect of
berberine based on experimental animal models of various cancers: a
systematic review and meta-analysis. BMC cancer. 2019;19(1):1-20.
55. Karatoprak GŞ, Küpeli Akkol E, Genç Y, Bardakcı H, Yücel Ç,
Sobarzo-Sánchez E. Combretastatins: an overview of structure, probable
mechanisms of action and potential applications. Molecules.
2020;25(11):2560.
56. Park Y, Woo SH, Seo SK, Kim H, Noh WC, Lee JK, et al. Ginkgetin
induces cell death in breast cancer cells via downregulation of the
estrogen receptor. Oncology Letters. 2017;14(4):5027-33.
57. Tripathi M, Reddy P, Rawat D. Noscapine and its analogues as
anti-cancer agents. Chem Biol Interface. 2014;4:1-22.
58. Chen L, Wang H-J, Xie W, Yao Y, Zhang Y-S, Wang H. Cryptotanshinone
inhibits lung tumorigenesis and induces apoptosis in cancer cells in
vitro and in vivo. Molecular medicine reports. 2014;9(6):2447-52.
Table 1. List of the anticancer drug classes and active
compounds in each class and common side effects.