Evaluation by maternal obesity
We also conducted an evaluation stratified by maternal obesity. Further
stratification by maternal obesity status revealed an increased risk for
T2DM over time for women with and without obesity, as demonstrated using
the Kaplan-Meier Hazard curves (Figure 2) and separate Cox regression
analysis (Table 2). For women with a BMI below 30
kg/m2, the FPG level associated with an increased risk
of T2DM relative to GDM was lower than for women with a BMI ≥30
kg/m2. Specifically, for women without obesity, FPG
levels over 100 mg/dl were a better predictor of T2DM compared to GDM
(7.17 (3.09-16.60) vs. 6.89 (4.46-10.63), aHR (95%CI)). For women with
obesity, the predictive performance of FPG in relation to T2DM surpassed
that of GDM, but only at FPG levels higher than 110 mg/dl (3.73
(1.32-7.21) vs. 3.27 ( 2.45-4.36) ), aHR (95%CI)).
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