Reproducibility and distribution of RSV and RV-specific IgG
levels
The reproducibility and distribution of RSV and RV-AB/C specific IgG
levels are presented in Table 2 and Figure 2. All values were above the
background levels. Additionally, the distribution of IgG levels to each
peptide under study are presented in Figure S2. RV-specific IgG levels
were higher among children from EGEA1 than in adults from EGEA2 for the
three species, while RSV-specific IgG levels were similar in children
and adults (Figure 2). Reproducibility was high with a mean CV at 0.12
for RV-specific IgG and 0.21 for RSV, and with excellent ICC (ICC ≥ 0.93
for all virus-specific IgG data). The correlations between IgG levels to
RSV and to RV-A/B/C were low (r≤0.27 in children and r≤0.42 in adults),
while the correlation was mild to strong between IgG levels across the
three RV species (r=0.32 between RV-B and RV-C to 0.72 between RV-A and
RV-C in children and r=0.53 to 0.81 in adults) (Figure S3).