3.2 NSC-Exos can improve the cognitive learning ability of MCAO model rats and has neuroprotective effect
​To test whether NSC-Exos improves cognitive function in rats, we tested their spatial learning and memory abilities using a Morris water maze. Compared with Sham group, IRI group and PBS group, the escape latency was prolonged, the swimming distance and the time required to explore the target quadrant were increased (P< 0.01), and the movement track was disorganized. Compared with IRI group and PBS group, the escape latency, swimming distance and exploration target quadrant time of NSC-Exos group were shortened (P< 0.01, Fig. 2a,b,c), and the direction of motion trajectory was more clear (Fig. 2d).