Pre-Allopurinol ​(n=32)​
Post- Allopurinol ​(n=32)​
No Allopurinol  (n=63)​
P-Value​
% Time in Range, median (IQR)   ​ 27 (15–58)​ 43 (26–55)​ –​ 0.03
% Time in Range, median (IQR)​ 27 (15–58)​ –​ 29 (20–53)​ 0.68​
% Time in Range, median (IQR)​ –​ 43 (26–55)​ 29 (20–53)​ 0.08​
6MMP:6TGN Ratio, median (IQR)​ 86.7 (54.8–127.7)​ 3.6 (1.7–11.4)​  –​ <0.0001
6MMP:6TGN Ratio, median (IQR)​ 86.7 (54.8–127.7)​  –​ 41.4 (10.9–83.5)​ 0.0002
6MMP:6TGN Ratio, median (IQR)​  –​ 3.6 (1.7–11.4)​ 41.4 (10.9–83.5)​ <0.0001
Abbreviations: 6MMP, 6-methylmercaptopurine; 6TGN, 6-thioguanine nucleotide; ANC, absolute neutrophil count; IQR, interquartile range. Bold text = statistical significance with a P-value <0.05 Abbreviations: 6MMP, 6-methylmercaptopurine; 6TGN, 6-thioguanine nucleotide; ANC, absolute neutrophil count; IQR, interquartile range. Bold text = statistical significance with a P-value <0.05 Abbreviations: 6MMP, 6-methylmercaptopurine; 6TGN, 6-thioguanine nucleotide; ANC, absolute neutrophil count; IQR, interquartile range. Bold text = statistical significance with a P-value <0.05 Abbreviations: 6MMP, 6-methylmercaptopurine; 6TGN, 6-thioguanine nucleotide; ANC, absolute neutrophil count; IQR, interquartile range. Bold text = statistical significance with a P-value <0.05 Abbreviations: 6MMP, 6-methylmercaptopurine; 6TGN, 6-thioguanine nucleotide; ANC, absolute neutrophil count; IQR, interquartile range. Bold text = statistical significance with a P-value <0.05