3.3 CUR regulates the inflammatory indicators associated with psoriasis-like lesions in mice
To further explore whether CUR regulates the inflammatory responses induced by IMQ, we explored the expression levels of multiple inflammatory indicators in mouse skin lesions by ELISA kit. As shown in Figure. 2C-D, CUR can significantly the epidermal expression levels of IL-6, IL-17A, IL-22, IL-23, TNF-α, TGF-β1 compared with IMQ group. In addition, the expression levels of IL-10 in CUR group were higher than in the IMQ group (Figure. 2C). The results demonstrated that CUR can repress the expression of inflammation factors related to psoriasis onset and development.