3.2 Sphingolipid receptor expression in the conjunctival cells:
Alteration in the sphingolipid metabolism was further supported by the increased S1P receptor 3 expressions (S1P3R) in conjunctival cells of VKC cases compared to control. S1P1R did not show significant change(Figure 2B) showing that the cellular uptake of S1P is S1P3R mediated. The receptor expression however did not show significant variation between NR-VKC and R-VKC (data not shown).