Acknowledgements
The authors would like to thank the Clinical Biological Resource Bank of Guangzhou Women and Children’s Medical Center for providing all the clinical samples. This study was supported by the Guangdong Natural Science Fund, China, grant number 2019A1515012061; the Guangzhou Science and Technology Program Project, China, grant numbers 201804010035, 201904010486; and the Guangzhou Medical And Health Technology Projects, China, grant numbers20191A011021, 20191A011033. Guangzhou Institute of Pediatrics/Guangzhou Women and Children’s Medical Center Fund, China, grant number YIP-2018-019, GCP-2019-003, YIP-2019-050, GCP-2019-006.