Table 3 Stratification analysis of susceptibility in sepsis patients
Variables CC+CT TT P-value a OR (95% CI) P-value Adjusted OR (95% CI) b P-value b
Patients/controls Patients/controls
Age, months Age, months Age, months Age, months Age, months Age, months Age, months Age, months
<12 219/271 14/13 0.468 1.333(0.614-2.894) 0.4681 1.327(0.609-2.888) 0.4763
12-60 179/312 15/11 0.0326 2.377(1.068-5.286) 0.0338 2.413(1.083-5.376) 0.0311
>60 45/69 2/2 0.6757 1.533(0.208-11.280) 0.6746 1.551(0.210-11.431) 0.6669
Gender Gender Gender Gender Gender Gender Gender Gender
Male 285/382 16/17 0.5161 1.262(0.627-2.540) 0.5152 1.244(0.617-2.508) 0.5411
Female 158/270 15/9 0.0137 2.848(1.218-6.658) 0.0157 2.868(1.226-6.714) 0.0152
Sepsis subtypes Sepsis subtypes Sepsis subtypes Sepsis subtypes Sepsis subtypes Sepsis subtypes Sepsis subtypes Sepsis subtypes
sepsis 90/652 9/26 0.0334 2.508(1.139-5.522) 0.0224 2.533(1.149-5.586) 0.0213
severe sepsis 272/652 18/26 0.1142 1.660(0.895-3.077) 0.1077 1.631(0.878-3.032) 0.1218
septic shock 81/652 4/26 0.7042 1.238(0.422-3.638) 0.6973 1.240(0.421-3.653) 0.6962
Prognosis
Survivors 367/652 27/26 0.0309 1.845(1.061-3.209) 0.0301 1.822(1.046-3.175) 0.0343
Non-survivors 76/652 4/26 0.6251 1.320(0.449-3.884) 0.6138 1.334(0.451-3.943) 0.6024
Number of organs with dysfunction, n (%) Number of organs with dysfunction, n (%) Number of organs with dysfunction, n (%) Number of organs with dysfunction, n (%) Number of organs with dysfunction, n (%) Number of organs with dysfunction, n (%)
1-2 260/652 16/26 0.1915 1.543(0.815-2.924) 0.1832 1.499(0.787-2.853) 0.2178
3 or more 89/652 6/26 0.2847 1.691(0.677-4.221) 0.2607 1.720(0.687-4.310) 0.2469
Note: a χ2 tests were used to determine differences in genotype distributions between the patients with sepsis and the healthy controls. b Adjusted for age and gender. The values are shown in bold if P < 0.05. Note: a χ2 tests were used to determine differences in genotype distributions between the patients with sepsis and the healthy controls. b Adjusted for age and gender. The values are shown in bold if P < 0.05. Note: a χ2 tests were used to determine differences in genotype distributions between the patients with sepsis and the healthy controls. b Adjusted for age and gender. The values are shown in bold if P < 0.05. Note: a χ2 tests were used to determine differences in genotype distributions between the patients with sepsis and the healthy controls. b Adjusted for age and gender. The values are shown in bold if P < 0.05. Note: a χ2 tests were used to determine differences in genotype distributions between the patients with sepsis and the healthy controls. b Adjusted for age and gender. The values are shown in bold if P < 0.05. Note: a χ2 tests were used to determine differences in genotype distributions between the patients with sepsis and the healthy controls. b Adjusted for age and gender. The values are shown in bold if P < 0.05. Note: a χ2 tests were used to determine differences in genotype distributions between the patients with sepsis and the healthy controls. b Adjusted for age and gender. The values are shown in bold if P < 0.05. Note: a χ2 tests were used to determine differences in genotype distributions between the patients with sepsis and the healthy controls. b Adjusted for age and gender. The values are shown in bold if P < 0.05.
Abbreviations: CI, confidence interval; OR, odds ratio. Abbreviations: CI, confidence interval; OR, odds ratio. Abbreviations: CI, confidence interval; OR, odds ratio. Abbreviations: CI, confidence interval; OR, odds ratio. Abbreviations: CI, confidence interval; OR, odds ratio. Abbreviations: CI, confidence interval; OR, odds ratio. Abbreviations: CI, confidence interval; OR, odds ratio. Abbreviations: CI, confidence interval; OR, odds ratio.