Pre-LAVi (p=0.38), pre-EF (p=0.66) and pre-RVSP (p=0.32) did not have significant crude (univariable) associations with EDV change. Pre-EDV (p<0.01) and pre-ESV (p<0.01) had significant crude associations with change in EDV and were therefore included in the adjusted model. Both were also significant predictors in the adjusted model (pre-EDV p<0.01; pre-ESV p<0.01). │Pre-GLS│ had a significant crude association with EDV change when linear (p=0.04) and quadratic (p=0.04) GLS terms were included in the model, as depicted in Figure 2. However, when adjusted for pre-EDV and pre-ESV, │Pre-GLS│ was no longer a significant predictor of EDV change (linear p=0.29, quadratic p=0.29). See Table V.
Table V. Predictors of EDV change in crude and adjusted models