Study Population:
All 189 patients who underwent MitraClip procedures between 2007-2019 at
our institution were reviewed retrospectively. Patients were included if
they were nonpregnant, greater than 18 years old, and had severe (4+) or
moderate/severe (3+) mitral regurgitation. Patients were excluded if
their pre- and post-procedural echocardiographs were outside the
pre-specified time window or if the images were inadequate.
Pre-procedural echocardiographs were identified as within 0-120 days
prior to the procedure and post-procedure echocardiographs as within
6-24months post procedure. Echocardiographs were considered inadequate
if the image quality was too poor to apply GLS or to acquire accurate 2D
measurements, or if one of the three views necessary for GLS
measurements (apical 4-Chamber, 3-Chamber, and 2-Chamber) was missing.
Any patient chart or echocardiogram with conflicting or uninterpretable
data was excluded. Complete echocardiographic data was available on 57
patients. See Figure 1 describing patient record selection.
Legend: Figure 1: Preferred Reporting Items for Systematic Reviews and
Meta-Analyses (PRISMA) Statement, Global longitudinal Strain (GLS),
Transthoracic echocardiogram (TTE)