Study Population:
All 189 patients who underwent MitraClip procedures between 2007-2019 at our institution were reviewed retrospectively. Patients were included if they were nonpregnant, greater than 18 years old, and had severe (4+) or moderate/severe (3+) mitral regurgitation. Patients were excluded if their pre- and post-procedural echocardiographs were outside the pre-specified time window or if the images were inadequate. Pre-procedural echocardiographs were identified as within 0-120 days prior to the procedure and post-procedure echocardiographs as within 6-24months post procedure. Echocardiographs were considered inadequate if the image quality was too poor to apply GLS or to acquire accurate 2D measurements, or if one of the three views necessary for GLS measurements (apical 4-Chamber, 3-Chamber, and 2-Chamber) was missing. Any patient chart or echocardiogram with conflicting or uninterpretable data was excluded. Complete echocardiographic data was available on 57 patients. See Figure 1 describing patient record selection.
Legend: Figure 1: Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement, Global longitudinal Strain (GLS), Transthoracic echocardiogram (TTE)