GLS was not a significant predictor of 10% change in EDV in the overall population (p=0.51) nor in the following sub-populations: top 50% EDV (p=0.42), degenerative MR (p=0.84), mixed MR (p=0.29), mixed and functional MR (p=0.41). See Table III for odds ratio estimates and 95% confidence intervals. However, higher │pre-GLS│ sample averages were noted in patients with at least 10% reduction in EDV compared to those without, as shown in Table IV.

Table III. GLS as a predictor of 10% change in EDV in various populations