Speckle Imaging Global Longitudinal Strain Data
Global longitudinal strain (GLS) was obtained with the Philips QLab
TomTec AutoSTRAIN© software. We measured endocardial
GLS from the apical 2-chamber, apical 3-chamber and apical 4-chamber
views, to generate the global value. GLS, typically a negative
percentage value as the deformation is a shortening dimension, was
reported in absolute value throughout this manuscript. The autostrain
measurement was first obtained, and then minor edits performed by the
clinician were applied to better approximate the endocardial boarder and
more accurately identify the mitral anulus. Two independent clinicians
performed edited autostrain GLS measurements on 20 echocardiograms on
two separate occasions to determine inter- and intra-rater reliability.