ABSTRACT:
We report a case of malignant mesenchymal spindle-cell neoplasia of the
skull, diagnosed in a female newborn at 13 days of age by biopsy and
subtotal resection.
Considering the good clinical condition, the age, tumor histology and
the risks associated with surgery and chemotherapy, we proposed a “wait
and see” approach with a close radiologic monitoring of the tumor
lesion. Surprisingly the tumor showed spontaneous regression both MRI
and ultrasound evaluations.
To date, after 12 months of observation, MRI showed sustained remission:
the infant recovered from surgery and maintains good clinical condition
while follow-up is ongoing.