Declarations:
Acknowledgement: We thank Mr Ravinder and Miss Kanika for helping us in the immunology laboratory.
Funding- The work was funded by the Post Graduate Institute of Medical Education and Research, Chandigarh via Special Research Grant 2017-18 for MD Thesis (L.P.480)
Conflicts of interest/Competing interests- None
Ethics approval- Approved by the Institute Ethics Committee (INT/IEC/2017/000299)
Consent to participate- Taken
Consent for publication- Taken
Authors’ contributions: SG collected the data, analysed and wrote the first draft. AR, JKS, NT and JBAT performed the laboratory investigations, helped in their interpretation and added intellectual content to the manuscript. LD, RR and RH managed the patients, helped in collecting data, analysis and writing the manuscript. KT conceptualized the project, supervised the data collection, analysis and finalized the manuscript. All authors approved the final draft.