3.1. | Study selection
Out of 79 identified publications in the initial search, 15 duplicated studies were excluded. After screening by title and abstract, 51 unrelated studies discarded due to the primary evaluation of inclusion criteria: unrelated title (n=33), animal study (n=16) and review (n=2) and 14 papers were retained for full-text review. One additional trial was extracted through hand-searching of reference lists of related reviews. Of these articles, 9 were excluded because of the following reasons: irrelevant (n=5), has no placebo-controlled group (n=1), without sufficient data for outcomes (n=3). Finally, 5 studies met all our inclusion criteria. Figure 1 demonstrates the process by which articles were selected.