Eligibility Criteria:
For inclusion, studies on MR-HIFU treatment of women with clinically
symptomatic uterine fibroids were reviewed. Treatment procedures that
did not target complete ablation (except for a five-mm protection margin
from the serosal surface) or ultrasound-guided HIFU systems were ruled
out.
The RCTs, prospective or Retrospective non-randomized, and cross-over
studies that considered the treatment of clinically symptomatic uterine
fibroids were included. The studies that did not have treatment
protocols regarded as complete removal of fibroid or used
ultrasound-guided HIFU were excluded. Also, animal studies, case
reports, and studies not reporting NPV were excluded.