• Results
Array analyses identified 273 differentially methylated CpG loci (≥0.2
β-value change) at initial diagnosis of PCOS, between women who did or
did not later develop diabetes. 19 of these sites demonstrated
differential methylation in the same direction in ≥five sample pairs.
Methylation in three of the candidates (cg11897887, cg02819655, and
cg25542007) showed the best concordance with corresponding array
β-values, and, most clearly differentiated ‘cases’ from ‘controls’.