Figure 2
Ixazomib triggers G2/M cell cycle arrest in esophageal cancer cells. (A, B) Ixazomib induced G2/M cell cycle arrest in Kyse150 and Kyse510 cells were treated with ixazomib at different concentration for 24 h, followed by PI staining and FACS analysis for cell cycle profile. (C), Distribution was analyzed by Modift and Graphpad software (lower panel). Values are the means ± SEM (n = 5-6). *P < 0.05 or **P < 0.01 indicates significant differences from the vehicle group as assessed by a two-tailed unpaired Student’s t test.