SLA: a new tumor immune stimulant
SLA (6ʹ-sulfate-β-D-Galp-(1,4)-β-D-Glcp-(1,1)-archaeol) is a new formulation of archaeosome, which was first proposed by McCluskie. Its composition is archaeosome core lipid modified by adding sulfated saccharide (Fig. 8) [85]. SLA has the characteristics of stabilizing archaea in extreme environments. Early studies on archaeal membranes explained the source of archaea. Archaea lack peptidoglycan and isoprenoid parts are ether connected to the l-glycerol backbone. In bacteria, esters are linked to fatty acid-derived hydrocarbon chains. Like liposomes, archaesome can constitute effective carrier vesicles for entrapped antigens, and the inherent stability and unique structure enable it more potential to be used as drug delivery carrier.