Title: Analgesic Effectiveness between Preemptive Intravenous Acetaminophen and Single-Shot Caudal Block in Paediatric Inguinal Hernia Repair

Authors:

Othman Siti Sarah Mmed(Anaesthesiology) (1), Zainal Abidin Huda Mmed(Anaesthesiology) (1), Mazlan Mohd Zulfakar Mmed(Anaesthesiology)(1), Abdul Mukmin Laila Mmed(Anaesthesiology)(1), Mohd Shah Mohd Shahrulsalam Mmed(Pead Surgery)(2), Nik Mohamad Nik Abdullah Mmed(Anaesthesiology)(1), Omar Mahamarowi Mmed(Anaesthesiology)(1)

1) Department of Anaesthesiology & Intensive Care, School of Medical Sciences, Hospital Universiti Sains Malaysia,16150 Kubang Kerian Kelantan, Malaysia.

2) Department of Surgery, School of Medical Sciences, Hospital Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan,

All authors declare no conflict of interest

Funding from Universiti Sains Malaysia

Address correspondence to:

Zainal Abidin, Huda;

Department of Anaesthesiology & Intensive Care,

Hospital Universiti Sains Malaysia,

16150 Kubang Kerian Kelantan, Malaysia.

hudaz82@gmail.com

+60199398443

What is already know:

-Paediatric Inguinal hernia repair is one of the most common surgery done in paediatric populations.

-Caudal block with amide local anaesthetic provides excellent pain relief for paediatric inguinal hernia repair.

-Intravenous acetaminophen has a high safety profile and used widely in paediatric patients.

What this study adds:

-Intravenous acetaminophen is equivocal to caudal block in paediatric inguinal hernia repair surgery.

We found no significant mean time difference for the first analgesic requirement and mean total opioid consumption between intravenous acetaminophen and caudal block