Sample size:
The sample size was determined based on BMI (mean = 28.9 and SD = 4.5)
as the primary outcome from a study conducted by Muscogiuri et al.(20);
The sample size was calculated using following formula:
N= [ (z1-α/2)2 ×
sd2]/d2 (α = 0.05, confidence
level of 95% and d = 2%) as 162 subjects. Considering the withdrawal
rate of 35%, 218 subjects were recruited.