Endoscopic Sinus Surgery
Necrotic tissues were endoscopically debrided until macroscopically healthy bleeding margins were reached. Patients were taken back to the operating room for further debridement whenever suspicion for continued infection remained. Of note, a more aggressive surgical approach was adopted in the latter years of the study, including endoscopic resection of the anterior skull base, clivus, pterygopalatine fossa and infratemporal fossa whenever these sites were involved.