Figure 3. Fer-1 hardly affects epileptic progression in FeCl3-induced PTE.
(A) Representative EEG recordings and power spectrum density in the chronic stage of PTE; (B) Quantification of EEG power spectra from day 19 to day 21 after FeCl3 injection in different groups; (C) Cumulative analysis of the effects of Fer-1 on the total power; (D) Effects of Fer-1 on the epileptiform spike frequency (marked with spikes per 10 min) from day 19 to day 21 after FeCl3 injection in different groups; (E) Indication of heat map of seizure activity over time (per day) per mouse treated with either vehicle or Fer-1 in the chronic stage of PTE; (F) Effects of Fer-1 on the cumulative spontaneous recurrent seizure (SRS) duration from day 19 to day 21 after FeCl3 injection. Data were expressed as mean ± SEM. *p<0.05 versus control group.