Author Contribution Statement
G.E.M and T.R.W conceived the study and participated in the overall design, and coordination of the study. G.E.M designed and performedin vitro experiments. S.A.A performed the immunoprecipitation and cell binding studies. E.K and R.B.K performed IHC analysis. E.K and M.J.D performed wire myography experiments, with R.D.R and T.K providing support and supervision for the ex vivo models, and V. B providing statistical support. G.E.M, G.M, N.M.G, N.S, M.A.K, L.C, C.S, and T.R.W designed and generated the SVEP1 knockout iPSC lines. G.E.M., N.J.S. and T.R.W supervised the overall project. G.E.M and T.R.W wrote the manuscript. All authors reviewed the manuscript.