SCREENING OF CHO-K1
ENDOGENOUS PROMOTERS FOR EXPRESSING RECOMBINANT PROTEINS IN MAMMALIAN
CELL CULTURES
Ileana Tossolini1,a,b, Agustina
Gugliotta1,a, Fernando López Díaz4,
Ricardo Kratje1, Claudio Prieto2,3
1 UNL, CONICET, FBCB (School of Biochemistry and
Biological Sciences), CBL (Biotechnological Center of Litoral), Ciudad
Universitaria, Ruta Nacional 168 Km 472.4, C.C. 242. (S3000ZAA), Santa
Fe, Argentina.
2 UNL, FBCB (School of Biochemistry and Biological
Sciences), CBL (Biotechnological Center of Litoral), Ciudad
Universitaria, Ruta Nacional 168 Km 472.4, C.C. 242. (S3000ZAA), Santa
Fe, Argentina.
3 Cellargen Biotech S.R.L., Antonia Godoy 6369, CP
3000, Santa Fe, Argentina.
4 Regulatory Biology Laboratory, Salk Institute for
Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037.
a These authors should be considered joint first
author.
b Present address: Instituto de Agrobiotecnología del
Litoral (CONICET-UNL), Cátedra de Biología Celular y Molecular, Facultad
de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral,
3000 Santa Fe, Argentina.